Basic Information
ID: ALA4035638
Type: Binding
Description: Antagonist activity at TLR4 (unknown origin) expressed in human AD293 cells assessed as inhibition of LPS/ATP-stimulated TLR4/NF-kB signaling pathway at 10 uM after 16 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4035638
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.63 | 3.10 | 3.10 |
| 490.64 | 2.98 | 2.98 |
| 563.49 | 3.80 | 3.80 |
| 730.85 | 5.39 | 5.39 |
| 656.77 | 2.37 | 2.37 |
| 540.65 | 4.20 | 4.20 |
| 670.80 | 5.37 | 5.37 |
| 669.77 | 6.11 | 6.11 |
| 498.57 | 2.61 | 2.61 |
| 502.60 | 2.19 | 2.19 |
| 808.92 | 8.44 | 8.44 |
| 624.77 | 6.20 | 6.20 |
| 612.72 | 4.32 | 4.32 |
| 500.59 | 2.40 | 2.40 |
| 685.77 | 5.27 | 5.27 |
| 941.04 | 6.98 | 6.98 |
| 567.12 | 3.77 | 3.77 |
| 552.66 | 3.67 | 3.67 |
| 494.63 | 3.93 | 3.93 |
| 714.85 | 6.22 | 6.22 |
| 779.67 | 6.23 | 6.23 |
| 798.80 | 5.95 | 5.95 |
| 654.80 | 6.21 | 6.21 |
| 960.60 | 7.34 | 7.34 |
| 850.87 | 6.75 | 6.75 |