Basic Information
ID: ALA4035648
Type: Binding
Description: Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated IL-6 mRNA level at 10 uM after 16 hrs by RT-PCR method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4035648
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.59 | 2.70 | 2.70 |
| 620.78 | 5.25 | 5.25 |
| 630.18 | 4.90 | 4.90 |
| 577.07 | 3.19 | 3.19 |
| 632.75 | 4.46 | 4.46 |
| 960.60 | 7.34 | 7.34 |
| 542.63 | 2.97 | 2.97 |