Basic Information
ID: ALA4035670
Type: Binding
Description: Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated NF-kB canonical signaling pathway by measuring decrease in IkBalpha phosphorylation at 10 uM after 3 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4035670
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 577.07 | 3.19 | 3.19 |
| 632.75 | 4.46 | 4.46 |