Basic Information
ID: ALA4035676
Type: Binding
Description: Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated NF-kB non-canonical signaling pathway by measuring decrease in p100/p52 phosphorylation at 10 uM after 3 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4035676
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 650.81 | 5.26 | 5.26 |
| 577.07 | 3.19 | 3.19 |