Assay Report Card

Basic Information

ID: ALA4035989

Type: Functional

Description: Anti-tumor activity against human MCF7 cells harboring PI3KCA E545K mutant xenografted in Swiss nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, po administered twice daily for 21 days measured post last dose relative to control

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
363.390.840.84