Assay Report Card

Basic Information

ID: ALA4036217

Type: Functional

Description: In-vivo inhibition of 11beta-HSD1 in cynomolgus monkey perirenal adipose tissue assessed as reduction in cortisol level at 3 mg/kg, po using [2H]-cortisone as substrate after 22 hrs by HPLC analysis relative to control

Organism: Macaca fascicularis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
460.575.015.01