Basic Information
ID: ALA4036219
Type: Functional
Description: In-vivo inhibition of 11beta-HSD1 in cynomolgus monkey abdominal subcutaneous adipose tissue assessed as reduction in cortisol level at 3 mg/kg, po using [2H]-cortisone as substrate after 22 hrs by HPLC analysis relative to control
Organism: Macaca fascicularis
Activity Charts
Bioactivity
Activity Types for Assay ALA4036219
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.57 | 5.01 | 5.01 |