Assay Report Card

Basic Information

ID: ALA4036297

Type: Binding

Description: Inhibition of MmpL3 in Mycobacterium massiliense isolate 1513 assessed as reduction in trehalose monomycolate by measuring decrease in mycolic acid transfer to cell envelope after 16 hrs using [1,2-14C]acetate labeled compounds by TLC analysis

Organism: Mycobacterium abscessus subsp. massiliense

Strain: isolate 1513

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
294.403.873.87
298.434.634.63
324.474.594.59
296.413.973.97