ID: ALA4036657
Type: ADME
Description: Unbound intrinsic clearance in mouse liver microsomes at 0.5 uM in presence of NADPH incubated for 5 to 30 mins by HPLC-MS/MS method
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: microsome
Bioactivity
Activity Types for Assay ALA4036657
CL
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
371.87 | 4.21 | 4.21 |
391.52 | 3.93 | 3.93 |
392.48 | 3.74 | 3.74 |
252.32 | 3.54 | 3.54 |
281.31 | 2.33 | 2.33 |
365.48 | 4.40 | 4.40 |
391.52 | 4.60 | 4.60 |
381.48 | 3.37 | 3.37 |
379.46 | 3.39 | 3.39 |
426.52 | 4.20 | 4.20 |
352.44 | 3.41 | 3.41 |
423.52 | 5.16 | 5.16 |
371.44 | 4.16 | 4.16 |
323.40 | 3.37 | 3.37 |
399.49 | 4.60 | 4.60 |
374.49 | 5.14 | 5.14 |
425.53 | 5.25 | 5.25 |
387.51 | 3.56 | 3.56 |
351.45 | 4.01 | 4.01 |
405.54 | 4.43 | 4.43 |
365.43 | 3.00 | 3.00 |
421.54 | 4.65 | 4.65 |
352.44 | 3.41 | 3.41 |
489.66 | 3.97 | 3.97 |
427.51 | 3.59 | 3.59 |
443.54 | 4.05 | 4.05 |
378.45 | 4.07 | 4.07 |
351.45 | 4.61 | 4.61 |
464.59 | 4.42 | 4.42 |
296.33 | 3.02 | 3.02 |
421.54 | 4.10 | 4.10 |
453.97 | 4.77 | 4.77 |
419.53 | 3.98 | 3.98 |
439.53 | 4.24 | 4.24 |
351.45 | 4.01 | 4.01 |
415.47 | 4.61 | 4.61 |
379.50 | 4.74 | 4.74 |
403.53 | 4.74 | 4.74 |