Basic Information
ID: ALA4036658
Type: ADME
Description: Unbound intrinsic clearance in human liver microsomes at 0.5 uM in presence of NADPH incubated for 5 to 30 mins by HPLC-MS/MS method
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4036658
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.87 | 4.21 | 4.21 |
| 391.52 | 3.93 | 3.93 |
| 392.48 | 3.74 | 3.74 |
| 252.32 | 3.54 | 3.54 |
| 281.31 | 2.33 | 2.33 |
| 365.48 | 4.40 | 4.40 |
| 391.52 | 4.60 | 4.60 |
| 381.48 | 3.37 | 3.37 |
| 379.46 | 3.39 | 3.39 |
| 426.52 | 4.20 | 4.20 |
| 352.44 | 3.41 | 3.41 |
| 423.52 | 5.16 | 5.16 |
| 371.44 | 4.16 | 4.16 |
| 323.40 | 3.37 | 3.37 |
| 399.49 | 4.60 | 4.60 |
| 374.49 | 5.14 | 5.14 |
| 425.53 | 5.25 | 5.25 |
| 387.51 | 3.56 | 3.56 |
| 351.45 | 4.01 | 4.01 |
| 405.54 | 4.43 | 4.43 |
| 365.43 | 3.00 | 3.00 |
| 421.54 | 4.65 | 4.65 |
| 352.44 | 3.41 | 3.41 |
| 489.66 | 3.97 | 3.97 |
| 427.51 | 3.59 | 3.59 |
| 443.54 | 4.05 | 4.05 |
| 378.45 | 4.07 | 4.07 |
| 351.45 | 4.61 | 4.61 |
| 464.59 | 4.42 | 4.42 |
| 296.33 | 3.02 | 3.02 |
| 421.54 | 4.10 | 4.10 |
| 453.97 | 4.77 | 4.77 |
| 419.53 | 3.98 | 3.98 |
| 439.53 | 4.24 | 4.24 |
| 351.45 | 4.01 | 4.01 |
| 415.47 | 4.61 | 4.61 |
| 379.50 | 4.74 | 4.74 |
| 403.53 | 4.74 | 4.74 |