Basic Information
ID: ALA4036700
Type: Binding
Description: Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction preincubated for 60 mins followed by cell stimulation measured after 24 hrs by 7AAD staining-based FACS analysis
Organism: Mus musculus
Strain: Balb/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4036700
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.62 | 4.22 | 4.22 |
| 527.65 | 4.47 | 4.47 |
| 496.57 | 3.42 | 3.42 |
| 593.73 | 3.78 | 3.78 |
| 611.72 | 3.91 | 3.91 |
| 653.76 | 3.68 | 3.68 |
| 666.85 | 4.59 | 4.59 |
| 635.77 | 3.54 | 3.54 |
| 501.61 | 4.60 | 4.60 |
| 524.63 | 4.45 | 4.45 |
| 496.57 | 3.42 | 3.42 |
| 495.58 | 4.54 | 4.54 |
| 624.81 | 4.82 | 4.82 |
| 497.56 | 2.81 | 2.81 |
| 471.59 | 5.09 | 5.09 |
| 509.61 | 4.58 | 4.58 |
| 510.60 | 3.66 | 3.66 |
| 525.61 | 4.41 | 4.41 |
| 497.56 | 2.81 | 2.81 |