Basic Information
ID: ALA4037231
Type: Binding
Description: Inhibition of recombinant Trypanosoma brucei N-terminal His6-tagged AdoMetDC/prozyme hetrodimer expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme activity assay
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA4037231
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.55 | 3.76 | 3.76 |
| 269.13 | 3.42 | 3.42 |
| 234.69 | 2.76 | 2.76 |
| 200.25 | 2.11 | 2.11 |
| 303.58 | 4.07 | 4.07 |
| 302.69 | 3.78 | 3.78 |
| 323.19 | 3.27 | 3.27 |
| 283.16 | 3.44 | 3.44 |
| 340.81 | 4.44 | 4.44 |
| 351.25 | 4.05 | 4.05 |
| 285.13 | 3.12 | 3.12 |
| 259.70 | 2.64 | 2.64 |
| 340.21 | 2.95 | 2.95 |
| 360.85 | 5.58 | 5.58 |
| 366.88 | 5.65 | 5.65 |
| 268.15 | 4.02 | 4.02 |
| 283.16 | 3.67 | 3.67 |
| 336.24 | 4.15 | 4.15 |
| 242.33 | 3.23 | 3.23 |
| 287.12 | 3.56 | 3.56 |
| 335.21 | 3.44 | 3.44 |
| 405.19 | 5.53 | 5.53 |
| 252.68 | 2.90 | 2.90 |
| 214.27 | 2.42 | 2.42 |
| 248.72 | 3.07 | 3.07 |
| 358.04 | 3.64 | 3.64 |
| 352.27 | 4.41 | 4.41 |
| 354.80 | 4.16 | 4.16 |
| 297.19 | 3.33 | 3.33 |
| 386.89 | 6.10 | 6.10 |
| 323.11 | 4.13 | 4.13 |
| 269.13 | 3.42 | 3.42 |
| 363.22 | 5.22 | 5.22 |
| 345.23 | 5.08 | 5.08 |
| 246.34 | 2.83 | 2.83 |
| 316.82 | 4.49 | 4.49 |
| 335.80 | 4.30 | 4.30 |
| 410.91 | 6.74 | 6.74 |
| 322.39 | 4.48 | 4.48 |
| 379.68 | 5.74 | 5.74 |
| 352.79 | 3.97 | 3.97 |
| 248.72 | 3.07 | 3.07 |
| 576.27 | 7.23 | 7.23 |
| 268.24 | 3.13 | 3.13 |
| 228.30 | 2.73 | 2.73 |
| 254.12 | 3.71 | 3.71 |
| 378.79 | 5.45 | 5.45 |
| 297.19 | 3.90 | 3.90 |
| 300.75 | 4.02 | 4.02 |
| 297.13 | 3.01 | 3.01 |
| 218.24 | 2.25 | 2.25 |
| 312.76 | 3.22 | 3.22 |
| 307.20 | 3.44 | 3.44 |
| 286.19 | 3.83 | 3.83 |
| 283.16 | 3.73 | 3.73 |
| 302.69 | 3.78 | 3.78 |
| 335.14 | 4.02 | 4.02 |
| 352.44 | 5.44 | 5.44 |
| 248.72 | 3.07 | 3.07 |
| 254.12 | 3.84 | 3.84 |
| 354.24 | 3.25 | 3.25 |
| 283.16 | 3.73 | 3.73 |
| 279.14 | 2.87 | 2.87 |
| 270.12 | 2.69 | 2.69 |
| 377.16 | 3.81 | 3.81 |
| 305.11 | 3.70 | 3.70 |
| 236.22 | 2.39 | 2.39 |
| 351.25 | 3.91 | 3.91 |
| 269.13 | 3.42 | 3.42 |
| 313.59 | 3.53 | 3.53 |
| 446.78 | 6.47 | 6.47 |
| 288.26 | 1.51 | 1.51 |
| 328.78 | 4.57 | 4.57 |
| 295.17 | 3.60 | 3.60 |
| 326.79 | 4.14 | 4.14 |
| 269.13 | 3.42 | 3.42 |
| 254.12 | 3.71 | 3.71 |
| 255.11 | 3.11 | 3.11 |
| 260.30 | 2.13 | 2.13 |
| 228.30 | 2.67 | 2.67 |
| 376.03 | 3.77 | 3.77 |
| 413.23 | 6.10 | 6.10 |
| 312.46 | 4.71 | 4.71 |
| 324.82 | 4.74 | 4.74 |
| 360.74 | 5.42 | 5.42 |
| 283.16 | 3.88 | 3.88 |
| 246.34 | 2.83 | 2.83 |
| 356.43 | 0.92 | 0.92 |
| 312.20 | 3.48 | 3.48 |
| 314.78 | 3.16 | 3.16 |
| 283.16 | 3.29 | 3.29 |
| 345.23 | 5.08 | 5.08 |
| 345.23 | 5.08 | 5.08 |
| 254.12 | 3.71 | 3.71 |
| 310.79 | 4.43 | 4.43 |
| 297.19 | 4.23 | 4.23 |
| 345.23 | 5.08 | 5.08 |