Basic Information
ID: ALA4037443
Type: Binding
Description: Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrest
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Chk1(ALA4630)
Document: ALA4033783
Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrest: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4037443
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.44 | 2.39 | 2.39 |
| 352.46 | 3.23 | 3.23 |
| 366.49 | 3.61 | 3.61 |
| 396.52 | 2.98 | 2.98 |
| 356.46 | 1.96 | 1.96 |
| 352.41 | 3.24 | 3.24 |
| 369.51 | 3.91 | 3.91 |
| 432.55 | 3.47 | 3.47 |
| 396.52 | 2.61 | 2.61 |
| 290.39 | 1.87 | 1.87 |
| 380.52 | 3.64 | 3.64 |
| 358.49 | 3.29 | 3.29 |
| 336.40 | 2.76 | 2.76 |
| 366.49 | 3.57 | 3.57 |
| 368.46 | 2.20 | 2.20 |
| 352.41 | 3.24 | 3.24 |
| 353.45 | 3.19 | 3.19 |
| 380.52 | 4.00 | 4.00 |
| 342.43 | 1.95 | 1.95 |
| 334.42 | 3.10 | 3.10 |
| 366.49 | 3.25 | 3.25 |
| 358.49 | 3.29 | 3.29 |
| 456.62 | 4.86 | 4.86 |
| 370.45 | 3.37 | 3.37 |
| 366.49 | 3.61 | 3.61 |
| 366.49 | 3.61 | 3.61 |
| 342.43 | 1.74 | 1.74 |
| 368.87 | 3.75 | 3.75 |