Inhibition of CHK1 in human H460 cells harboring dominant negative p53 construct assessed as potentiation of gemcitabine-induced antiproliferative act...

Basic Information

ID: ALA4037449

Type: Binding

Description: Inhibition of CHK1 in human H460 cells harboring dominant negative p53 construct assessed as potentiation of gemcitabine-induced antiproliferative activity relative to control

Format: BAO_0000219

Organism: Homo sapiens

Target:  Serine/threonine-protein kinase Chk1(ALA4630)

Document:  ALA4033783

Inhibition of CHK1 in human H460 cells harboring dominant negative p53 construct assessed as potentiation of gemcitabine-induced antiproliferative activity relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
344.442.392.39
352.463.233.23
366.493.613.61
370.453.373.37