Basic Information
ID: ALA4037459
Type: Functional
Description: Abrogation of topotecan-induced G2 phase arrest in human HCT116 cells xenografted in mouse hollow fiber model assessed as ratio of cell levels at G2 phase to G1 phase at 10 mg/kg, iv after 30 hrs relative to control
Format: BAO_0000218
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA4033783
Abrogation of topotecan-induced G2 phase arrest in human HCT116 cells xenografted in mouse hollow fiber model assessed as ratio of cell levels at G2 phase to G1 phase at 10 mg/kg, iv after 30 hrs relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4037459
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.46 | 3.23 | 3.23 |
| 366.49 | 3.61 | 3.61 |
| 370.45 | 3.37 | 3.37 |