ID: ALA4037493
Type: Functional
Description: Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4037493
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
183.10 | -1.03 | -1.03 |
217.18 | -1.04 | -1.04 |
239.18 | 0.17 | 0.17 |
239.16 | -0.47 | -0.47 |
364.25 | 0.37 | 0.37 |
363.22 | 0.57 | 0.57 |
334.22 | 0.36 | 0.36 |
363.17 | 1.45 | 1.45 |
324.25 | 0.72 | 0.72 |
317.23 | 0.45 | 0.45 |
302.22 | 1.17 | 1.17 |
308.18 | 0.25 | 0.25 |
315.26 | 0.95 | 0.95 |
379.22 | 0.27 | 0.27 |
317.24 | 0.62 | 0.62 |
341.22 | 1.77 | 1.77 |
348.25 | 0.67 | 0.67 |
323.27 | 0.69 | 0.69 |
274.21 | 0.14 | 0.14 |
307.19 | 0.04 | 0.04 |
331.18 | 1.36 | 1.36 |
386.22 | 1.68 | 1.68 |
363.22 | 0.57 | 0.57 |
403.33 | 0.49 | 0.49 |
352.67 | 1.31 | 1.31 |
334.22 | 0.36 | 0.36 |
318.22 | 0.66 | 0.66 |
324.25 | 0.72 | 0.72 |
288.24 | 0.33 | 0.33 |
298.24 | 0.62 | 0.62 |
336.21 | 0.80 | 0.80 |
318.22 | 0.66 | 0.66 |
350.22 | 0.07 | 0.07 |
317.23 | 0.45 | 0.45 |
363.22 | 0.57 | 0.57 |
334.22 | 0.36 | 0.36 |
332.25 | 0.97 | 0.97 |
334.22 | 0.36 | 0.36 |
301.24 | 0.96 | 0.96 |