Basic Information
ID: ALA4037499
Type: Functional
Description: Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037499
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 183.10 | -1.03 | -1.03 |
| 239.18 | 0.17 | 0.17 |
| 239.16 | -0.47 | -0.47 |
| 364.25 | 0.37 | 0.37 |
| 347.26 | 0.21 | 0.21 |
| 313.25 | 0.63 | 0.63 |
| 290.21 | -0.15 | -0.15 |
| 407.36 | 2.46 | 2.46 |
| 334.22 | 0.36 | 0.36 |
| 363.17 | 1.45 | 1.45 |
| 324.25 | 0.72 | 0.72 |
| 386.22 | 1.68 | 1.68 |
| 348.25 | 0.67 | 0.67 |
| 348.25 | 0.88 | 0.88 |
| 302.22 | 1.17 | 1.17 |
| 401.40 | 2.84 | 2.84 |
| 289.22 | 0.46 | 0.46 |
| 274.21 | 0.14 | 0.14 |
| 378.27 | 0.76 | 0.76 |
| 429.45 | 3.62 | 3.62 |
| 334.22 | 0.36 | 0.36 |
| 378.27 | 0.76 | 0.76 |
| 318.22 | 0.66 | 0.66 |
| 348.25 | 0.67 | 0.67 |
| 290.21 | -0.15 | -0.15 |
| 352.21 | 0.50 | 0.50 |
| 333.23 | 0.15 | 0.15 |
| 364.25 | 0.37 | 0.37 |
| 363.26 | 0.34 | 0.34 |
| 318.22 | 0.87 | 0.87 |
| 352.67 | 1.31 | 1.31 |
| 348.25 | 0.67 | 0.67 |
| 364.25 | 0.37 | 0.37 |
| 318.22 | 0.66 | 0.66 |
| 303.25 | 0.76 | 0.76 |
| 421.39 | 2.50 | 2.50 |
| 318.22 | 0.66 | 0.66 |
| 288.24 | 0.33 | 0.33 |
| 336.21 | 0.80 | 0.80 |
| 334.22 | 0.36 | 0.36 |
| 378.27 | 0.76 | 0.76 |
| 318.22 | 0.66 | 0.66 |
| 350.22 | 0.07 | 0.07 |
| 351.32 | 0.15 | 0.15 |
| 352.21 | 0.50 | 0.50 |
| 457.42 | 3.61 | 3.61 |
| 332.25 | 0.97 | 0.97 |
| 295.26 | -0.21 | -0.21 |
| 352.21 | 0.50 | 0.50 |