Basic Information
ID: ALA4037524
Type: Binding
Description: Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV protease tagged human CXCL1-stimulated beta-arrestin recruitment by CCF4-AM-fluorescence based FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037524
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.28 | 4.66 | 4.66 |
| 437.35 | 3.39 | 3.39 |
| 428.94 | 3.62 | 3.62 |
| 437.35 | 3.39 | 3.39 |
| 495.95 | 4.08 | 4.08 |
| 375.88 | 2.05 | 2.05 |
| 428.94 | 3.47 | 3.47 |
| 414.91 | 3.23 | 3.23 |
| 386.90 | 3.85 | 3.85 |
| 407.28 | 2.62 | 2.62 |
| 372.87 | 3.15 | 3.15 |
| 376.84 | 3.37 | 3.37 |
| 429.97 | 3.39 | 3.39 |
| 428.94 | 3.62 | 3.62 |
| 372.87 | 3.46 | 3.46 |
| 445.46 | 4.00 | 4.00 |
| 414.91 | 3.23 | 3.23 |
| 407.28 | 2.62 | 2.62 |
| 407.32 | 4.02 | 4.02 |
| 468.02 | 4.07 | 4.07 |
| 460.96 | 3.96 | 3.96 |
| 407.32 | 4.02 | 4.02 |
| 374.89 | 3.54 | 3.54 |
| 437.90 | 3.20 | 3.20 |
| 414.91 | 2.96 | 2.96 |
| 388.92 | 3.93 | 3.93 |
| 389.91 | 2.44 | 2.44 |
| 376.86 | 2.53 | 2.53 |
| 426.92 | 3.23 | 3.23 |
| 453.99 | 3.68 | 3.68 |
| 442.97 | 3.86 | 3.86 |
| 477.96 | 3.78 | 3.78 |
| 374.89 | 3.68 | 3.68 |
| 442.97 | 4.01 | 4.01 |
| 404.89 | 3.80 | 3.80 |
| 446.93 | 3.57 | 3.57 |
| 414.91 | 3.23 | 3.23 |
| 453.32 | 3.70 | 3.70 |
| 377.47 | 3.07 | 3.07 |
| 402.90 | 3.08 | 3.08 |
| 442.97 | 3.86 | 3.86 |
| 358.85 | 3.07 | 3.07 |
| 374.89 | 3.54 | 3.54 |
| 404.92 | 3.31 | 3.31 |
| 423.32 | 3.00 | 3.00 |
| 386.90 | 3.68 | 3.68 |
| 394.83 | 3.66 | 3.66 |
| 453.32 | 3.70 | 3.70 |
| 456.99 | 4.25 | 4.25 |
| 376.86 | 2.53 | 2.53 |
| 418.87 | 3.14 | 3.14 |
| 423.32 | 3.00 | 3.00 |
| 372.87 | 3.46 | 3.46 |
| 426.84 | 4.00 | 4.00 |
| 482.05 | 4.46 | 4.46 |
| 360.86 | 3.29 | 3.29 |
| 390.89 | 2.92 | 2.92 |
| 393.29 | 3.63 | 3.63 |
| 386.90 | 3.85 | 3.85 |
| 427.95 | 3.14 | 3.14 |
| 390.86 | 3.76 | 3.76 |
| 432.90 | 3.53 | 3.53 |
| 459.97 | 3.48 | 3.48 |
| 414.91 | 3.23 | 3.23 |
| 388.92 | 3.93 | 3.93 |
| 440.87 | 4.39 | 4.39 |
| 388.92 | 3.93 | 3.93 |