Basic Information
ID: ALA4037528
Type: Binding
Description: Antagonist activity at CXCR2 in human whole blood assessed as inhibition of GROalpha-stimulated CD11b upregulation preincubated for 15 mins followed by GROalpha stimulation measured after 15 mins by FITC-staining based FACS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037528
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.43 | 2.90 | 2.90 |
| 428.94 | 3.62 | 3.62 |
| 495.95 | 4.08 | 4.08 |
| 428.94 | 3.47 | 3.47 |
| 414.91 | 3.23 | 3.23 |
| 429.97 | 3.39 | 3.39 |
| 428.94 | 3.62 | 3.62 |
| 445.46 | 4.00 | 4.00 |
| 414.91 | 3.23 | 3.23 |
| 468.02 | 4.07 | 4.07 |
| 460.96 | 3.96 | 3.96 |
| 437.90 | 3.20 | 3.20 |
| 414.91 | 2.96 | 2.96 |
| 426.92 | 3.23 | 3.23 |
| 453.99 | 3.68 | 3.68 |
| 442.97 | 3.86 | 3.86 |
| 477.96 | 3.78 | 3.78 |
| 442.97 | 4.01 | 4.01 |
| 404.89 | 3.80 | 3.80 |
| 446.93 | 3.57 | 3.57 |
| 414.91 | 3.23 | 3.23 |
| 377.47 | 3.07 | 3.07 |
| 402.90 | 3.08 | 3.08 |
| 442.97 | 3.86 | 3.86 |
| 394.83 | 3.66 | 3.66 |
| 456.99 | 4.25 | 4.25 |
| 418.87 | 3.14 | 3.14 |
| 482.05 | 4.46 | 4.46 |
| 386.90 | 3.85 | 3.85 |
| 427.95 | 3.14 | 3.14 |
| 432.90 | 3.53 | 3.53 |
| 459.97 | 3.48 | 3.48 |
| 414.91 | 3.23 | 3.23 |
| 440.87 | 4.39 | 4.39 |