Basic Information
ID: ALA4037616
Type: ADME
Description: Ratio of passive permeability in presence of dual P-gp/BCRP inhibitor GF120918 to absence of GF120918 in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins by Transwell assay
Organism: Canis lupus familiaris
Cell type: MDCK2-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA4037616
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.46 | 4.00 | 4.00 |
| 453.99 | 3.68 | 3.68 |
| 442.97 | 3.86 | 3.86 |
| 377.47 | 3.07 | 3.07 |
| 394.83 | 3.66 | 3.66 |
| 386.90 | 3.85 | 3.85 |
| 427.95 | 3.14 | 3.14 |
| 414.91 | 3.23 | 3.23 |
| 440.87 | 4.39 | 4.39 |