Assay Report Card

Basic Information

ID: ALA4037818

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as CYP450 mediated-O-demethylated 2-(4-hydroxyphenyl)-7-(trideuteriomethoxy)-5H-pyrazolo[4,3-c]quinolin-3-one metabolite formation after 60 mins by LC-MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
324.352.842.84