Assay Report Card

Basic Information

ID: ALA4037832

Type: ADME

Description: Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 2-(6-hydroxy-3-pyridyl)-7-(trideuteriomethoxy)-5H-pyrazolo[4,3-c]quinolin-3-one metabolite formation after 60 mins by LC-MS analysis

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.342.232.23