Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 7-bromo-2-(4-hydroxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one ...

Basic Information

ID: ALA4037836

Type: ADME

Description: Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 7-bromo-2-(4-hydroxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one metabolite formation after 60 mins by LC-MS analysis

Format: BAO_0000019

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Unchecked(ALA612545)

Document: ALA4033790

Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 7-bromo-2-(4-hydroxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one metabolite formation after 60 mins by LC-MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4037836

Drug metabolism

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
373.22	3.59	3.59

Parent Molecular Weight

ALogP

Polar Surface Area

373.22

3.59

Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 7-bromo-2-(4-hydroxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one ...

Basic Information

Activity Charts

Compound Summary