Assay Report Card

Basic Information

ID: ALA4037837

Type: ADME

Description: Drug metabolism in mouse liver microsomes assessed as CYP450 mediated-O-demethylated 8-chloro-2-(3-hydroxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one metabolite formation after 60 mins by LC-MS analysis

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
328.773.483.48