Basic Information
ID: ALA4037917
Type: Binding
Description: Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPilight pyrophosphate-detection based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037917
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 263.34 | 3.90 | 3.90 |
| 335.41 | 3.05 | 3.05 |
| 279.34 | 3.14 | 3.14 |
| 258.71 | 3.38 | 3.38 |
| 295.73 | 4.54 | 4.54 |
| 265.32 | 2.69 | 2.69 |
| 330.43 | 2.71 | 2.71 |
| 299.76 | 3.59 | 3.59 |
| 228.68 | 3.88 | 3.88 |
| 314.39 | 1.93 | 1.93 |
| 236.28 | 2.65 | 2.65 |
| 264.33 | 3.30 | 3.30 |
| 347.42 | 3.19 | 3.19 |
| 234.26 | 3.11 | 3.11 |
| 242.71 | 4.19 | 4.19 |
| 350.42 | 2.89 | 2.89 |
| 285.73 | 3.24 | 3.24 |
| 249.32 | 3.13 | 3.13 |
| 363.42 | 2.43 | 2.43 |
| 190.20 | 1.74 | 1.74 |
| 253.69 | 3.75 | 3.75 |
| 260.34 | 2.35 | 2.35 |
| 252.28 | 1.98 | 1.98 |
| 334.42 | 3.65 | 3.65 |
| 251.29 | 3.09 | 3.09 |
| 363.42 | 2.43 | 2.43 |
| 280.33 | 2.54 | 2.54 |
| 195.22 | 2.62 | 2.62 |
| 311.77 | 3.78 | 3.78 |
| 271.71 | 2.98 | 2.98 |
| 288.35 | 1.54 | 1.54 |
| 335.41 | 3.05 | 3.05 |
| 299.76 | 3.63 | 3.63 |
| 229.67 | 3.28 | 3.28 |