Basic Information
ID: ALA4037934
Type: Binding
Description: Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP production preincubated for 30 mins followed by LPS addition measured after 16 hrs by NF-kappaB reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037934
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 691.60 | 3.97 | 3.97 |
| 747.71 | 5.53 | 5.53 |
| 759.85 | 7.09 | 7.09 |