Basic Information
ID: ALA4037937
Type: Binding
Description: Inhibition of TLR4/MD2 interaction in human THP1 cells assessed as reduction of LPS-induced IL8 production at 10 uM preincubated for 1 hr followed by LPS stimulation measured after 16 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037937
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 691.60 | 3.97 | 3.97 |
| 747.71 | 5.53 | 5.53 |
| 859.92 | 8.65 | 8.65 |
| 759.85 | 7.09 | 7.09 |