Basic Information
ID: ALA4037938
Type: Binding
Description: Inhibition of TLR4/MD2 interaction in human THP1 cells assessed as reduction of LPS-induced p65 NF-kappaB phosphorylation up to 10 uM preincubated for 1 hr followed by LPS stimulation measured after 16 hrs by immunoblot method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4037938
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 747.71 | 5.53 | 5.53 |