Basic Information
ID: ALA4038091
Type: Binding
Description: Inverse agonist activity at RORgammat (unknown origin) expressed in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL-17 ROR response element driven-bright-glo luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4038091
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.52 | 4.13 | 4.13 |
| 518.56 | 4.22 | 4.22 |
| 509.58 | 4.02 | 4.02 |
| 482.55 | 4.38 | 4.38 |
| 495.55 | 3.63 | 3.63 |
| 509.58 | 4.02 | 4.02 |
| 495.55 | 3.63 | 3.63 |
| 505.59 | ||
| 510.57 | 2.53 | 2.53 |
| 504.61 | ||
| 509.58 | 4.02 | 4.02 |
| 488.53 | 4.59 | 4.59 |
| 510.57 | 3.52 | 3.52 |
| 509.58 | 4.02 | 4.02 |
| 483.54 | 3.77 | 3.77 |