Inhibition of KRAS-PDEdelta interaction in unstimulated KRAS-dependent human Capan1 cells assessed as downregulation of ERK phosphorylation at Thr202/...

Basic Information

ID: ALA4038112

Type: Binding

Description: Inhibition of KRAS-PDEdelta interaction in unstimulated KRAS-dependent human Capan1 cells assessed as downregulation of ERK phosphorylation at Thr202/Tyr204 at 20 uM after 1 hr by Western blot analysis

Format: BAO_0000019

Organism: Homo sapiens

Target:  Phosphodiesterase 6D(ALA3860)

Document:  ALA4033798

Inhibition of KRAS-PDEdelta interaction in unstimulated KRAS-dependent human Capan1 cells assessed as downregulation of ERK phosphorylation at Thr202/Tyr204 at 20 uM after 1 hr by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
457.584.214.21
581.716.756.75