Assay Report Card

Basic Information

ID: ALA4038177

Type: ADME

Description: Drug metabolism in rat plasma assessed as (5R,8S,11S,14S,17S,20S,23R)-29-[[(2R)-2-acetamido-3-[[(1S)-1-(hydroxymethyl)-2-[[(1S)-2-[(2S)-2-[[(1S)-2-hydroxy-1-methyl-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-3-oxo-propyl]sulfanylmethyl]-5-amino-14-(3-amino-3-oxo-propyl)-17-(carboxymethyl)-11-(1H-imidazol-5-ylmethyl)-8,20-diisobutyl-6,9,12,15,18,21-hexaoxo-3,25-dithia-7,10,13,16,19,22-hexazabicyclo[25.3.1]hentriaconta-1(31),27,29-triene-23-carboxylic acid metabolite formation at 50 uM after 18 hrs by MALDI-TOF analysis

Organism: Rattus norvegicus

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1687.99