Assay Report Card

Basic Information

ID: ALA4039307

Type: Functional

Description: In vivo receptor occupancy at mGlu5 in baboon assessed as unbound plasma concentration required to show 50% effect up to 0.56 mg/kg, iv administered over 20 mins for 30 mins prior to [18F]-FPEB addition by microPET imaging analysis

Organism: Papio anubis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.302.762.76