Basic Information
ID: ALA4039337
Type: ADME
Description: Invivo prodrug activation in heart of of BALB/C nude mouse xenografted with human MDA-MB-231 cells assessed as FAP-alpha mediated (S)-((3S,5R,8R,9S,10S,11S,13R,14S,17R)-11,14-dihydroxy-10,13-dimethyl-12-oxo-17-(2-oxo-2H-pyran-5-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl) 2-amino-3-(1H-indol-3-yl)propanoate formation at 40 umol/L by LC-MS/MS analysis
Organism: Mus musculus
Strain: BALB/C
Tissue: Heart
Activity Charts
Bioactivity
Activity Types for Assay ALA4039337
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 891.03 | 5.07 | 5.07 |