Basic Information
ID: ALA4040006
Type: Binding
Description: Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded DNA containing a 3'-phosphotyrosine as substrate after 15 mins by PAGE analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosyl-DNA phosphodiesterase 1(ALA1075138)
Document: ALA4038309
Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded DNA containing a 3'-phosphotyrosine as substrate after 15 mins by PAGE analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4040006
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 422.46 | 2.05 | 2.05 |
| 438.48 | 2.84 | 2.84 |
| 411.89 | 3.66 | 3.66 |
| 436.49 | 2.39 | 2.39 |
| 367.38 | 2.37 | 2.37 |
| 454.94 | 3.35 | 3.35 |
| 423.90 | 3.76 | 3.76 |
| 423.44 | 2.48 | 2.48 |
| 381.41 | 2.76 | 2.76 |
| 383.84 | 2.88 | 2.88 |
| 397.86 | 3.27 | 3.27 |
| 404.40 | 3.04 | 3.04 |
| 453.93 | 3.12 | 3.12 |
| 395.43 | 3.14 | 3.14 |
| 438.92 | 2.57 | 2.57 |
| 407.45 | 3.24 | 3.24 |
| 439.90 | 2.99 | 2.99 |
| 437.47 | 2.60 | 2.60 |
| 420.86 | 3.56 | 3.56 |