Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional ...

Basic Information

ID: ALA4040045

Type: Binding

Description: Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 1 to 1000 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay

Format: BAO_0000219

Organism: Mus musculus

Target:  Probable protein-cysteine N-palmitoyltransferase porcupine(ALA1255164)

Document:  ALA4038310

Inhibition of mouse PORCN expressed in human HT1080 cells coexpressing Wnt/beta-catenin assessed as decrease in beta-catenin-mediated transcriptional activity at 1 to 1000 nM after 24 hrs in presence of Wnt3a by luciferase reporter gene assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
404.431.361.36