Basic Information
ID: ALA4040184
Type: Functional
Description: Antiviral activity against CXCR4-tropic HIV-1 NL4-3 infected in human TZM-bl cells assessed as inhibition of virus-induced cytopathic effect preincubated with cells for 30 mins followed by viral infection measured after 48 hrs in presence of p-24 HIV-1 Ag by luciferase reporter gene assay
Organism: Human immunodeficiency virus 1
Strain: NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4040184
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.22 | -0.05 | -0.05 |
| 321.20 | -0.40 | -0.40 |
| 321.20 | -0.40 | -0.40 |
| 296.19 | -0.67 | -0.67 |
| 305.21 | -0.10 | -0.10 |
| 305.21 | -0.10 | -0.10 |
| 296.19 | -0.67 | -0.67 |
| 281.18 | -0.68 | -0.68 |
| 636.66 | 4.81 | 4.81 |
| 636.66 | 4.81 | 4.81 |
| 627.65 | 4.24 | 4.24 |
| 612.64 | 4.22 | 4.22 |
| 612.64 | 4.22 | 4.22 |
| 281.18 | -0.68 | -0.68 |
| 652.66 | 4.10 | 4.10 |
| 627.65 | 4.24 | 4.24 |
| 652.66 | 4.10 | 4.10 |