Basic Information
ID: ALA4040187
Type: Functional
Description: Antiviral activity against CXCR4-tropic HIV-1 NL4-3 infected in human PHA-stimulated PBMC assessed as inhibition of viral replication by measuring reduction in p24 antigen production preincubated with cells for 30 mins followed by viral infection measured on day 10 post infection in presence of IL-2 by ELISA
Organism: Human immunodeficiency virus 1
Strain: NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4040187
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.22 | -0.05 | -0.05 |
| 321.20 | -0.40 | -0.40 |
| 321.20 | -0.40 | -0.40 |
| 635.52 | 3.04 | 3.04 |
| 305.21 | -0.10 | -0.10 |
| 305.21 | -0.10 | -0.10 |
| 476.47 | 2.97 | 2.97 |
| 636.66 | 4.81 | 4.81 |
| 636.66 | 4.81 | 4.81 |
| 652.66 | 4.10 | 4.10 |
| 652.66 | 4.10 | 4.10 |