Basic Information
ID: ALA4040232
Type: ADME
Description: Inhibition of recombinant human NEP using pyr-1-apelin-13 as substrate assessed as peptide degradation at 1 mM preincubated for 10 mins followed by substrate addition measured after 72 hrs by LC-MS analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Neprilysin(ALA1944)
Document: ALA4038314
Inhibition of recombinant human NEP using pyr-1-apelin-13 as substrate assessed as peptide degradation at 1 mM preincubated for 10 mins followed by substrate addition measured after 72 hrs by LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4040232
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2188.42 | ||
| 1596.70 | ||
| 2201.46 | ||
| 2201.46 | ||
| 2201.46 | ||
| 1596.70 | ||
| 1582.67 | ||
| 2187.43 | ||
| 2188.42 | ||
| 1583.66 | ||
| 1583.66 | ||
| 1596.70 |