Basic Information
ID: ALA4040377
Type: ADME
Description: Inhibition of CYP3A4 (unknown origin) at 10 uM
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4038320
Inhibition of CYP3A4 (unknown origin) at 10 uM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4040377
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.72 | 3.10 | 3.10 |
| 466.47 | 4.44 | 4.44 |
| 463.49 | 3.97 | 3.97 |
| 553.62 | 5.35 | 5.35 |
| 285.74 | 3.13 | 3.13 |
| 414.47 | 3.42 | 3.42 |
| 432.92 | 4.07 | 4.07 |
| 285.74 | 3.13 | 3.13 |
| 398.47 | 3.72 | 3.72 |
| 281.32 | 2.49 | 2.49 |
| 299.76 | 3.17 | 3.17 |
| 398.47 | 3.75 | 3.75 |
| 466.47 | 4.44 | 4.44 |
| 442.52 | 3.53 | 3.53 |
| 373.49 | 4.77 | 4.77 |
| 371.44 | 4.10 | 4.10 |
| 397.48 | 4.32 | 4.32 |
| 463.49 | 3.74 | 3.74 |
| 383.46 | 4.01 | 4.01 |
| 523.52 | 4.40 | 4.40 |
| 426.52 | 4.29 | 4.29 |
| 285.74 | 3.13 | 3.13 |
| 496.49 | 3.89 | 3.89 |
| 342.79 | 3.09 | 3.09 |
| 400.51 | 4.75 | 4.75 |
| 330.37 | 1.13 | 1.13 |
| 494.48 | 4.29 | 4.29 |
| 462.46 | 3.55 | 3.55 |
| 343.39 | 4.27 | 4.27 |
| 412.50 | 3.84 | 3.84 |
| 405.48 | 3.45 | 3.45 |
| 428.50 | 3.43 | 3.43 |
| 370.42 | 3.73 | 3.73 |
| 281.32 | 2.49 | 2.49 |
| 418.89 | 4.06 | 4.06 |
| 382.47 | 4.41 | 4.41 |
| 329.79 | 2.67 | 2.67 |
| 383.46 | 4.01 | 4.01 |
| 385.43 | 3.67 | 3.67 |
| 281.32 | 2.49 | 2.49 |
| 384.44 | 3.41 | 3.41 |
| 399.46 | 3.80 | 3.80 |
| 414.47 | 3.42 | 3.42 |
| 412.50 | 3.90 | 3.90 |
| 265.32 | 2.16 | 2.16 |
| 308.35 | 2.44 | 2.44 |
| 495.51 | 4.71 | 4.71 |
| 398.47 | 3.42 | 3.42 |
| 383.46 | 4.01 | 4.01 |
| 567.64 | 5.74 | 5.74 |
| 384.44 | 4.28 | 4.28 |
| 457.49 | 3.00 | 3.00 |
| 299.77 | 3.44 | 3.44 |
| 426.52 | 4.46 | 4.46 |
| 251.29 | 2.48 | 2.48 |
| 420.50 | 2.96 | 2.96 |
| 466.47 | 4.44 | 4.44 |
| 474.57 | 4.93 | 4.93 |
| 418.89 | 4.31 | 4.31 |
| 357.42 | 4.06 | 4.06 |
| 285.74 | 3.13 | 3.13 |
| 467.46 | 3.83 | 3.83 |
| 308.35 | 1.84 | 1.84 |
| 414.47 | 3.42 | 3.42 |
| 539.59 | 5.31 | 5.31 |
| 385.43 | 3.67 | 3.67 |
| 414.47 | 2.90 | 2.90 |
| 302.79 | 3.81 | 3.81 |
| 459.55 | 5.68 | 5.68 |
| 400.51 | 4.75 | 4.75 |
| 302.79 | 3.81 | 3.81 |
| 398.47 | 3.34 | 3.34 |
| 330.37 | 1.13 | 1.13 |
| 299.72 | 2.77 | 2.77 |
| 398.47 | 3.45 | 3.45 |
| 435.44 | 3.09 | 3.09 |
| 382.47 | 4.62 | 4.62 |
| 384.44 | 4.28 | 4.28 |