Assay Report Card

Basic Information

ID: ALA4040516

Type: Functional

Description: Antagonist activity at human metabotropic glutamate receptor 5 expressed in HEK293 cells assessed as inhibition of glutamate-induced Ca2+ internalization after 1 hr by fluo-4-AM dye based fluorescence assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
451.885.585.58
439.356.466.46
459.305.525.52
356.834.724.72