Basic Information
ID: ALA4040525
Type: Functional
Description: Antagonist activity at rat metabotropic glutamate receptor 6 expressed in CHO cell membranes assessed as inhibition of glutamate-induced [35S]GTPgammaS binding preincubated for 30 mins followed by [35S]GTPgammaS addition measured after 30 mins by Topcount scintillation counting method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4040525
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.88 | 5.58 | 5.58 |
| 439.35 | 6.46 | 6.46 |
| 459.30 | 5.52 | 5.52 |
| 356.83 | 4.72 | 4.72 |