Basic Information
ID: ALA4041133
Type: Binding
Description: Allosteric inhibition of recombinant human N-terminal GST-tagged WNK1 catalytic domain (1 to 491 residues) expressed in baculovirus expression system using fluorescein-labeled OSR1 peptide as substrate after 3 hrs by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase WNK1(ALA1075173)
Document: ALA4038341
Allosteric inhibition of recombinant human N-terminal GST-tagged WNK1 catalytic domain (1 to 491 residues) expressed in baculovirus expression system using fluorescein-labeled OSR1 peptide as substrate after 3 hrs by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4041133
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.96 | 3.86 | 3.86 |
| 421.93 | 4.37 | 4.37 |
| 425.58 | 6.37 | 6.37 |
| 399.54 | 5.76 | 5.76 |
| 437.54 | 4.87 | 4.87 |
| 486.02 | 5.91 | 5.91 |
| 424.59 | 6.98 | 6.98 |
| 462.41 | 4.51 | 4.51 |
| 443.57 | 6.51 | 6.51 |
| 394.56 | 6.97 | 6.97 |
| 465.42 | 4.51 | 4.51 |
| 476.00 | 6.29 | 6.29 |