Basic Information
ID: ALA4041207
Type: Binding
Description: Inhibition of SMO V404M mutant in gefitinib resistant human HCC827 cells assessed as decrease in GLI1 activity at 2 to 60 uM in presence of SMO agonist SAG by GLI1 luciferase reporter assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4041207
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.36 | 5.77 | 5.77 |
| 375.41 | 4.90 | 4.90 |
| 517.61 | 5.68 | 5.68 |
| 632.66 | 5.77 | 5.77 |
| 352.31 | 1.72 | 1.72 |
| 560.49 | 5.35 | 5.35 |
| 517.46 | 5.91 | 5.91 |
| 507.34 | 3.58 | 3.58 |