Assay Report Card

Basic Information

ID: ALA4041614

Type: Binding

Description: Inhibition of HCV genotype 1b NK5.1 NS5A in infected human Huh 7.5.1 cells assessed as reduction in viral RNA replication by measuring combination index in presence of NS5B inhibitor sofosbuvir at ED50 incubated for 3 days by luciferase reporter gene assay

Organism: Hepatitis C virus subtype 1b

Strain: NK5.1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
834.955.265.26
856.914.444.44