Basic Information
ID: ALA4041727
Type: Functional
Description: Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding up to 10 uM preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method relative to 5-HT
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Serotonin 1a (5-HT1a) receptor(ALA214)
Document: ALA4041469
Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding up to 10 uM preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method relative to 5-HT: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4041727
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 247.38 | 3.37 | 3.37 |
| 385.51 | 2.53 | 2.53 |
| 343.42 | 2.82 | 2.82 |
| 343.42 | 2.82 | 2.82 |
| 389.50 | 4.01 | 4.01 |
| 419.52 | 4.02 | 4.02 |
| 449.55 | 4.03 | 4.03 |
| 449.55 | 4.03 | 4.03 |
| 449.55 | 4.03 | 4.03 |
| 419.52 | 4.02 | 4.02 |
| 419.52 | 4.02 | 4.02 |
| 389.50 | 4.01 | 4.01 |
| 389.50 | 4.01 | 4.01 |
| 434.49 | 3.92 | 3.92 |
| 403.52 | 4.32 | 4.32 |
| 449.55 | 4.00 | 4.00 |
| 423.94 | 4.67 | 4.67 |
| 405.49 | 3.72 | 3.72 |
| 390.48 | 3.41 | 3.41 |