Assay Report Card

Basic Information

ID: ALA4041784

Type: Functional

Description: Trypanocidal activity against Trypanosoma cruzi RA tripamastigote bloodstream forms infected in Balb/c mouse assessed as mouse survival at 100 mg/kg, po administered on day 9 post infection for 5 consecutive days measured daily during compound dosing up to 45 days post infection

Organism: Trypanosoma cruzi

Strain: RA

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
260.251.111.11
342.363.223.22
365.364.334.33