Basic Information
ID: ALA4041853
Type: Binding
Description: Inhibition of Staphylococcus aureus DNA gyrase B using relaxed pNO1 DNA as substrate incubated for 30 mins and measured by sybrGOLD staining based fluorescence assay
Organism: Staphylococcus aureus
Activity Charts
Bioactivity
Activity Types for Assay ALA4041853
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 397.48 | 2.74 | 2.74 |
| 541.24 | 4.04 | 4.04 |
| 479.17 | 2.51 | 2.51 |
| 480.16 | 3.45 | 3.45 |
| 376.24 | 2.22 | 2.22 |
| 365.26 | -0.97 | -0.97 |
| 493.20 | 2.76 | 2.76 |
| 447.54 | 3.75 | 3.75 |
| 499.20 | 3.72 | 3.72 |
| 451.12 | 2.03 | 2.03 |
| 499.20 | 3.72 | 3.72 |
| 505.21 | 3.11 | 3.11 |
| 293.32 | 0.60 | 0.60 |
| 357.41 | 1.84 | 1.84 |
| 398.25 | 2.77 | 2.77 |
| 423.06 | 1.35 | 1.35 |
| 374.83 | 1.07 | 1.07 |
| 479.17 | 2.37 | 2.37 |
| 391.43 | 2.90 | 2.90 |
| 479.17 | 2.60 | 2.60 |
| 465.14 | 2.42 | 2.42 |
| 479.17 | 2.51 | 2.51 |
| 465.14 | 2.21 | 2.21 |
| 513.19 | 3.36 | 3.36 |
| 379.42 | 2.61 | 2.61 |
| 451.12 | 2.03 | 2.03 |
| 451.12 | 2.13 | 2.13 |
| 336.78 | -0.01 | -0.01 |
| 383.45 | 2.65 | 2.65 |
| 390.27 | 2.30 | 2.30 |
| 343.43 | 3.30 | 3.30 |
| 555.27 | 4.13 | 4.13 |
| 329.36 | 1.36 | 1.36 |
| 465.14 | 2.42 | 2.42 |
| 491.18 | 3.02 | 3.02 |
| 479.17 | 2.67 | 2.67 |
| 310.79 | 0.28 | 0.28 |
| 437.09 | 1.39 | 1.39 |
| 433.51 | 3.67 | 3.67 |
| 465.14 | 2.12 | 2.12 |
| 451.12 | 1.82 | 1.82 |
| 343.38 | 1.75 | 1.75 |
| 343.38 | 1.45 | 1.45 |
| 423.06 | 1.30 | 1.30 |
| 307.35 | 0.69 | 0.69 |
| 405.45 | 2.99 | 2.99 |
| 465.14 | 2.28 | 2.28 |
| 324.77 | -0.08 | -0.08 |
| 465.14 | 2.12 | 2.12 |