Basic Information
ID: ALA4041937
Type: Functional
Description: Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP production at 1 uM by [3H]cAMP competition binding based scintillation counting method relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Adenosine A2b receptor(ALA255)
Document: ALA4041491
Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP production at 1 uM by [3H]cAMP competition binding based scintillation counting method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4041937
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.14 | 2.74 | 2.74 |
| 424.89 | 5.97 | 5.97 |
| 276.30 | 3.24 | 3.24 |
| 304.31 | 3.24 | 3.24 |
| 419.49 | 4.83 | 4.83 |
| 420.47 | 5.32 | 5.32 |
| 391.43 | 4.71 | 4.71 |
| 418.46 | 4.88 | 4.88 |
| 344.37 | 3.66 | 3.66 |
| 279.10 | 2.33 | 2.33 |
| 266.26 | 2.83 | 2.83 |
| 316.36 | 3.65 | 3.65 |
| 390.45 | 5.32 | 5.32 |
| 328.38 | 3.58 | 3.58 |
| 316.36 | 3.65 | 3.65 |
| 316.36 | 3.65 | 3.65 |
| 200.20 | 1.57 | 1.57 |
| 344.37 | 3.66 | 3.66 |
| 396.48 | 5.38 | 5.38 |
| 404.47 | 5.17 | 5.17 |
| 392.46 | 5.22 | 5.22 |
| 530.53 | 6.83 | 6.83 |
| 330.35 | 3.34 | 3.34 |
| 404.47 | 5.62 | 5.62 |
| 329.36 | 4.04 | 4.04 |
| 408.44 | 5.45 | 5.45 |
| 314.35 | 3.65 | 3.65 |
| 315.34 | 3.04 | 3.04 |
| 328.38 | 3.96 | 3.96 |
| 319.16 | 2.75 | 2.75 |
| 240.27 | 1.99 | 1.99 |
| 420.47 | 5.32 | 5.32 |
| 304.31 | 3.24 | 3.24 |
| 210.24 | 1.98 | 1.98 |
| 276.30 | 3.24 | 3.24 |
| 286.34 | 3.65 | 3.65 |
| 380.41 | 4.91 | 4.91 |
| 320.78 | 4.30 | 4.30 |