Basic Information
ID: ALA4041968
Type: Binding
Description: Inhibition of recombinant Leishmania donovani DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting
Organism: Leishmania donovani
Activity Charts
Bioactivity
Activity Types for Assay ALA4041968
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.31 | 2.35 | 2.35 |
| 264.12 | 3.70 | 3.70 |
| 339.40 | 2.54 | 2.54 |
| 289.32 | 0.93 | 0.93 |
| 362.42 | 0.77 | 0.77 |
| 321.38 | 3.06 | 3.06 |
| 293.25 | 3.42 | 3.42 |
| 395.94 | 4.50 | 4.50 |
| 325.37 | 2.39 | 2.39 |
| 273.32 | 1.92 | 1.92 |
| 331.81 | 2.81 | 2.81 |
| 309.32 | 4.14 | 4.14 |
| 297.67 | 4.07 | 4.07 |
| 360.44 | 1.98 | 1.98 |
| 381.48 | 2.77 | 2.77 |
| 357.85 | 2.16 | 2.16 |
| 346.42 | 1.11 | 1.11 |
| 354.41 | 2.76 | 2.76 |
| 397.48 | 2.08 | 2.08 |
| 268.28 | 2.21 | 2.21 |
| 297.36 | 2.22 | 2.22 |
| 377.84 | 4.75 | 4.75 |
| 316.75 | 3.62 | 3.62 |
| 344.80 | 2.55 | 2.55 |
| 257.68 | 2.86 | 2.86 |
| 397.48 | 2.08 | 2.08 |
| 230.66 | 2.44 | 2.44 |
| 242.24 | 0.78 | 0.78 |
| 272.70 | 2.86 | 2.86 |
| 397.48 | 2.08 | 2.08 |
| 264.29 | 2.89 | 2.89 |
| 376.38 | 4.10 | 4.10 |
| 241.22 | 2.35 | 2.35 |
| 400.28 | 3.82 | 3.82 |
| 283.29 | 2.36 | 2.36 |
| 299.34 | 0.95 | 0.95 |
| 381.48 | 2.77 | 2.77 |
| 297.67 | 4.07 | 4.07 |
| 350.34 | 3.60 | 3.60 |
| 279.13 | 3.29 | 3.29 |
| 297.36 | 2.16 | 2.16 |
| 244.69 | 2.63 | 2.63 |
| 328.44 | 3.30 | 3.30 |
| 280.36 | 3.60 | 3.60 |
| 321.38 | 3.06 | 3.06 |
| 319.29 | 3.93 | 3.93 |
| 268.71 | 3.53 | 3.53 |
| 330.42 | 2.09 | 2.09 |
| 326.36 | 2.28 | 2.28 |
| 381.44 | 2.48 | 2.48 |
| 310.36 | 2.39 | 2.39 |
| 344.80 | 2.55 | 2.55 |
| 323.70 | 4.57 | 4.57 |
| 288.38 | 2.64 | 2.64 |
| 293.25 | 3.42 | 3.42 |
| 397.48 | 2.08 | 2.08 |
| 281.21 | 3.55 | 3.55 |
| 283.34 | 1.97 | 1.97 |
| 400.44 | 4.06 | 4.06 |
| 350.34 | 3.60 | 3.60 |
| 316.79 | 3.23 | 3.23 |