Basic Information
ID: ALA4042261
Type: Binding
Description: Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21(DE3) using H3K4me2 as substrate preincubated for 1 hr followed by substrate addition by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4042261
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.44 | 2.56 | 2.56 |
| 271.35 | 2.31 | 2.31 |
| 364.49 | 3.74 | 3.74 |
| 401.50 | 4.65 | 4.65 |
| 398.54 | 2.86 | 2.86 |
| 477.55 | 4.37 | 4.37 |
| 553.61 | 3.11 | 3.11 |
| 340.46 | 2.13 | 2.13 |
| 384.51 | 1.84 | 1.84 |
| 347.45 | 4.47 | 4.47 |
| 329.43 | 2.52 | 2.52 |
| 523.65 | 6.30 | 6.30 |
| 387.47 | 4.34 | 4.34 |
| 391.46 | 4.17 | 4.17 |
| 379.49 | 3.42 | 3.42 |
| 431.48 | 4.04 | 4.04 |
| 361.47 | 4.78 | 4.78 |
| 405.46 | 4.48 | 4.48 |
| 526.63 | 4.43 | 4.43 |
| 365.44 | 4.61 | 4.61 |
| 422.60 | 4.18 | 4.18 |
| 432.47 | 2.15 | 2.15 |
| 414.54 | 4.86 | 4.86 |
| 607.70 | 6.27 | 6.27 |
| 437.53 | 4.49 | 4.49 |
| 345.46 | 1.89 | 1.89 |
| 392.45 | 2.27 | 2.27 |
| 421.92 | 5.00 | 5.00 |
| 412.48 | 4.22 | 4.22 |
| 466.37 | 5.11 | 5.11 |
| 369.49 | 3.20 | 3.20 |